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miRCURY LNA™ microRNA Array Analysis Software

Fast and accurate analysis of miRCURY LNA™ microRNA Array data using specifically adapted versions of BioDiscovery’s ImaGene® 9 and Nexus Expression™ 3.

  • ImaGene® 9 and Nexus Expression™ 3 in a package specifically adapted to Exiqon’s microarrays
  • Easy workflow for fast and accurate analysis of your miRCURY LNA™ microRNA Array data – no bioinformatics skills required
  • Best-in-class grid placement, automatic analysis and quality check of all spots
  • Quick and easy identification of differentially expressed microRNAs
  • Direct links to microRNAs in miRBase and TargetScan 

Leading-edge microarray analysis software

Exiqon offers a comprehensive microarray analysis package specifically suited for the analysis of miRCURY LNA™ microRNA Array data. The package consists of the well-known ImaGene® 9 and Nexus Expression™ 3 from BioDiscovery as well as settings files for rapid and easy analysis of Exiqon microarrays.

It lets researchers quickly identify differentially expressed microRNAs and analyze expression patterns across samples.
  • A complete data analysis tool – converts raw signal values into meaningful information visualized by common statistical methods through a user-friendly workflow.

ImaGene® 9

ImaGene® is a very powerful tool for microarray image analysis. Through an intuitive interface, it lets the user extract signal intensities from the scanned array and flag (poor) spots either automatically or manually (Figure 1). ImaGene® can also be used for easy visualization of microarray data in scatter or M-A plots (Figure 2).

Highlights include:
  • Advanced spot finding and grid placement
  • Automatic analysis and quality check of all spots
  • Interactive spot checking
  • Intuitive interface and navigation
  • Scanner, array and system independent
  • Integrated settings file for convenient analysis of Exiqon’s miRCURY LNA™ microRNA Arrays
  • A quality control template specifically designed for Exiqon's microarrays.

Nexus Expression™ 3

Nexus Expression™ is a very feature packed but easy to use program for the analysis of microarray experiments. Using a simple workflow, raw data from ImaGene® is background-subtracted and normalized, after which the data can be visualized in heat maps and differentially expressed microRNAs identified (Figures 3 & 4).

Highlights include:
  • Simple but powerful workflow – No bioinformatics/programming skills required
  • One click workflow, with direct links to microRNAs in miRBase and TargetScan
  • Combines replicate measurements
  • Identifies differentially expressed microRNAs
  • Clusters analysis: clusters sample groups or microRNAs
Figure 1 ImaGene® 9 screenshot
Fast and accurate spot identification. (Click to learn more)


Figure 2 ImaGene® 9 screenshot
Excellent data visualization. (Click to learn more)

Figure 3 Nexus Expression™ 2 screenshot
Up or down regulated microRNAs are easily identified. (Click to learn more)

Figure 4 Nexus Expression™ 2 screenshot
Flexible clustering of data. (Click to learn more)

System requirements

ImaGene® 9
  • Platforms Supported: Windows 9x/Nt4/Win2k/WinXP, Linux, OS X
  • Minimum: 700 MHz Pentium or G4, 256 MB RAM
  • Recommended: 2.0 GHz or faster Intel® Core™ 2 Duo processor, 1024 or more MB RAM

Nexus Expression™ 3
  • Platforms Supported: Windows Win2k/WinXP, OS X
  • Minimum: 1.0 GHz Pentium or G4, 512 MB RAM
  • Recommended: 2.0 GHz or faster Intel® Core™ 2 Duo processor, 1024 or more MB RAM

Get started with the miRCURY LNA™ microRNA Array Analysis Software

1. Buy a license. Use the web shop below or contact us

2. Follow instructions provided by email for how to install the software and activate your license using these links:
ImaGene installer download links: 3. Download settings files for Exiqon arrays (right click on link and choose "Save Target as") 4. Optional step if Exiqon's 7th or 6th gen array is not found in Nexus. For some versions of Nexus Expression™ 2, Exiqon's 7th and 6th gen arrays are not found in the list of arrays. If this is the case, download and extract the appropriate file and follow the instructions found in the Read-me.txt file:

Quality control of your data

As an exlusive offer to Exiqon customers, we are offering a Microsoft Excel 2007 QC template to analyze all slides in an array experiment. This template can be used to calculate various QC parameters and to determine if slides need to be removed from the experiment.

Get a free demo of the miRCURY LNA™ microRNA Array Analysis Software

1. Request demo license keys using our contact form . License keys valid for 2 weeks will be sent by email.

2. Follow instructions provided by email for how to install the software and activate your license using these links:
ImaGene installer download links: 3. Download settings files for Exiqon arrays (right click on link and choose "Save Target as") 4. The programs are now ready for use. You may receive an alert concerning "update eligibility". Please ignore this message.

5. Download sample array data (optional). Use this data to quickly get started with your array data analysis:


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