miRNA Since the discovery of microRNA (miRNA) a few years ago, these small RNAs have been shown to be involved in a large number of very important biological processes including embryonic development, cancer and cardiovascular disease. The number of miRNA publications has grown at an exponential rate and more scientists than ever are involved in miRNA research.
The study of microRNAs is complicated by the fact that they are too short for most traditional methods of analysis. At Exiqon we have solved this problem by incorporating Locked Nucleic Acid (LNA™) in our range of products. The high affinity of LNA™ for its complementary sequence makes it the perfect choice for detecting small RNAs such as miRNAs. Learn more about LNA™ .
Below is a short presentation of some of our miRCURY LNA™ products.
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miRNA Microarray Analysis Featuring Tm normalized capture probes, our miRCURY LNA™ microRNA Arrays offer unrivaled sensitivity and specificity. Read more |
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miRNA Northern Blotting Highly specific miRCURY microRNA LNA™ Detection Probes, designed by our bioinformatics team, are available for all miRBase annotated microRNAs. We also design custom probes and offer suitable control probes. Read more |
miRNA Quantitation by qPCR Our new miRNA PCR system offers the best available combination of performance and ease-of-use on the miRNA real-time PCR market. The combination of a Universal RT reaction and LNA™-enhanced PCR primers results in unmatched sensitivity and specificity. The Ready-to-use miRNA PCR panels enable fast and easy miRNA expression profiling. Read more |
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In situ Hybridization of miRNAs Our highly specific and sensitive miRCURY LNA™ microRNA Detection Probes are available for all sequences annotated in miRBase. In addition, control detection probes and custom designed probes are also available. Read more |
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miRNA Inhibition We offer miRCURY LNA™ microRNA inhibitors for functional analysis of miRNA - both in vitro and in vivo. In addition, a Tm normalized miRNA inhibitor library featuring the highest coverage of human miRNAs on the market is available for high-throughput analysis. All products are based on the LNA™-technology for superior efficacy, specificity and biostability. . Read more |
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miRNA Services For fast miRNA analysis, Exiqon offers services on sample isolation, profiling by array and qPCR, and in situ hybridization.Our miRNA profiling service covers everything from an initial consultation to the final data analysis. The service is carried out in state of the art laboratories using our latest generation of miRCURY LNA™ microRNA products. Read more |
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