Dr. Dorina Veliceasa, from the department of Urology at the Northwestern University Feinberg School of Medicine, discusses the use of the miRCURY LNA™ microRNA PCR system in her investigation of tumor angiogenesis in endothelial cells. Dr. Veliceasa discusses the challenges of qPCR monitoring of microRNA species, including the importance of endogenous controls, and offers advice to other researchers interested in this method of determining microRNA expression levels.