microRNA detection probes with superior sensitivity and specificity
miRCURY LNA™ microRNA Detection Probes for Northern Blotting offer very high binding affinity, single-nucleotide discrimination and remarkable signal-to-noise ratios, resulting in highly specific and sensitive microRNA detection. The probes are designed with optimal LNA™ positioning to achieve high sequence specificity, low secondary structure and minimal self-annealing.
Pre-designed miRCURY LNA™ microRNA Detection Probes for Northern blotting are available for most known microRNAs in invertebrates, vertebrates and plants annotated in miRBase
. The probes are available with a selection of 3’-end, 5’-end and double (3’ and 5’) labels: DIG, biotin, and fluorescein (FAM version). “Ready-to-label” probes designed for custom labeling are also available.
Pre-designed miRCURY LNA™ microRNA Detection Probes are provided in 1 nmol quantity, delivered dried down. For larger amounts, 10 nmol probes are available as custom miRCURY LNA™ microRNA Detection Probes. Please contact us
Higher sensitivity with double-labeled probes
For researchers who wish to detect microRNAs on Northern blots by non-radioactive methods, we recommend the use of double (3’ and 5’) DIG-labeled or fluorescein probes.
NoteCustom miRCURY LNA™ microRNA Detection Probes
are available for your own microRNAs and other small RNAs, including pre-microRNAs. Positive and negative control probes
are also available.
To find a particular miRCURY LNA™ microRNA Detection Probe, please use the search function below.