Exiqon
Home Search Contact Print Sign In
 
 
Products Services Applications Resource Center Ordering About Exiqon Investor
microRNA Research
RNA Research
DNA Research
Custom Oligos
Other Reagents
RNA Isolation
Microarray Analysis
Real-time PCR
Northern Blotting
In Situ Hybridization
Functional Analysis
RNA Preparation
Microarray analysis
Real-time PCR
In Situ Hybridization
Antisense
SNP Detection
Microarray Analysis
In Situ Hybridization
LNA Phosphoramidites
A2 Quencher
RNA Isolation Services
microRNA Array Services
microRNA PCR Services
microRNA ISH Services
Custom Pharma Service
Isolation
Microarray Analysis
Northern Blotting
Real-time PCR
In Situ Hybridization
Functional Analysis
SNP Detection
RNA
microRNA
RNA
DNA
microRNA
microRNA
mRNA
microRNA
Other RNAs
DNA
microRNA
RNA
DNA
MicroRNA Research
RNA Research
Other reagents
Technology Base
Oligo design tools
Exiqon E-talk
MicroRNA
Research Guide
Array Data Analysis
qPCR Data Analysis
Tech notes and Manuals
Scientific Publications
Application Stories
Bioinformatics
Technical Literature and Manuals
Scientific Publications
Application Stories
Bioinformatics
Technical Literature and Manuals
Scientific Publications
Oligo modifications
LNA™
AQ-link
Order microRNA products
Order custom oligos
Distributors
General Information
Contact
Company profile
History
Management
Board of Directors
Awards & Partnerships
Sign up to Newsletter
Newsletter Back Issues
 

Custom miRCURY LNA™ Detection Probes

Ina K. Dahlsveen, Product manager Take advantage of Exiqon’s expertise in designing LNA™-enhanced detection probes targeting custom RNA sequences


Ina K. Dahlsveen, Ph.D., Product ManagerBack
  • Unmatched detection of small RNA molecules by in situ hybridization and Northern blotting
  • Superior specificity and sensitivity
  • Designed by our expert team for optimal LNA™ content and positioning
  • Minimal secondary structure and self-complementarity

Coverage

Our custom detection probes are available with a selection of 3’ and 5’ labels (DIG*, biotin, fluorescein, amino). “Ready-to-label” probes designed for custom labeling are also available. For ordering, price information and requests for alternative labels, please contact us.

In designing a probe, we recommend using sequences 20-25 nucleotides in length. A probe of this length uses the advantages of the LNA™ technology by resulting in high melting temperatures (between 70-85°C), good mismatch discrimination, and high binding specificity, while avoiding unacceptable secondary structure and self-complementarity. However, slightly shorter or longer probes can often be designed within the standard design criteria.

Note

Before submitting your order, please check if a pre-designed detection probe targeting your sequence is available . Pre-designed miRCURY LNA™ microRNA Detection Probes are available for all microRNA sequences annotated in miRBase.

*Licensed from Roche Diagnostics GmbH


Before submitting your order, please . Pre-designed miRCURY LNA™ microRNA Detection Probes are available for all microRNA sequences annotated in miRBase.
"Exiqon is one of the leading suppliers for miRNA-related products"

Dr. Liming Luan Dr. Liming Luan at Vanderbilt University Medical Center in Nashville studies the role of microRNAs in normal and pathological conditions of the skin.

Read full story...

"I was intrigued by this interesting technology, which is very different from other available technologies."

Dr. Mircea Ivan at Indiana University School of Medicine studies the role of microRNAs in hypoxia. Here he describes why his lab chose Exiqon's detection probes.

Read full story...

“We got some beautiful data and spectacular images”

"We generated a complete catalogue of images showing the temporal and spatial expression patterns of 115 conserved microRNAs in zebrafish embryos."

Prof Ronald H. A. Plasterk, Hubrecht Laboratory, The Netherlands

Read full story...

Dylan Sweetman “Following the success of LNA™ probes as demonstrated in Plasterk’s lab, we decided to take the same approach”

Dr. Dylan Sweetman is working in Dr. Andrea Münsterberg’s group at the University of East Anglia, School of Biological Sciences. The group investigates cellular and molecular mechanisms that underlie embryonic development.

Read full story...
Parker Antin “LNA™ technology is superior to any other for the detection of small RNA species”

Dr. Parker Antin’s lab at the University of Arizona runs a large scale in situ hybridization database project to determine the expression patterns for all differentially expressed genes in the chicken embryo. Find out what the challenges were with this huge project and how they were overcome.

Read full story...
This is a custom LNA™ product. Please contact us for further information and ordering.
Our global technical support team will respond within 2 business days.
Application stories
MicroRNA research guide
Contact us
  Privacy   Sitemap   Legal