Home > DNA Research > In Situ Hybridization > Pre-validated LNA™ FISH Probes
Fast, sensitive and specific detection of chromosomal DNA sequences with pre-validated LNA™-enhanced probes.
Although fluorescence in situ hybridization (FISH) has proven useful in cytogenetics, it has traditionally been a time-consuming method with limitations in sensitivity and resolution. Our high-affinity LNA™ FISH Probes offer fast, sensitive and specific detection of chromosomal DNA.
Pre-validated LNA™-enhanced FISH probes targeting human classical satellite-2 repeats, human telomeres and human centromere alpha-satellite sequences are available. These probes are available with 5’-biotin or 5’-fluorescein labels. For custom-made LNA™-probes targeting other chromosomal sequences, please contact Exiqon.
The high affinity of LNA™-enhanced probes for their complementary sequences make them ideal for chromosomal FISH. These probes give strong signals even after hybridization periods of less than one hour.
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