HomeOrderContactPrint

Recent Papers on the Applications of LNA

The following is a list of publications that have come out in the last 6 months describing the use of LNA in research. For a comprehensive, searchable list of published references describing the use of LNA, please go to our publications database in our Tech Center.

Rune Thomsen, Peter S. Nielsen, Torben H. Jensen
Dramatically improved RNA in situ hybridization signals using LNA-modified probes
RNA, Nov 2005; 11(11): 1745 - 1748.

Erno Wienholds, Wigard P. Kloosterman, Eric Miska, Ezequiel Alvarez-Saavedra, Eugene Berezikov, Ewart de Bruijn, Robert H. Horvitz, Sakari Kauppinen, and Ronald H. A. Plasterk
MicroRNA Expression in Zebrafish Embryonic Development
Science, May 2005; 10.1126/science.1114519.

Sara K. Hansen, Eva-Maria D. Nielsen, Jakob Ek, Gitte Andersen, Charlotte Glümer, Bendix Carstensen, Peter Mouritzen, Thomas Drivsholm, Knut Borch-Johnsen, Torben Jřrgensen, Torben Hansen, and Oluf Pedersen
Analysis of Separate and Combined Effects of Common Variation in KCNJ11 and PPARG on Risk of Type 2 Diabetes
J. Clin. Endocrinol. Metab., Jun 2005; 90: 3629 - 3637.

Charles-Henri Lecellier, Patrice Dunoyer, Khalil Arar, Jacqueline Lehmann-Che, Stephanie Eyquem, Christophe Himber, Ali Saďb, and Olivier Voinnet
A Cellular MicroRNA Mediates Antiviral Defense in Human Cells
Science, Apr 2005; 308: 557 - 560.

Donald Pfaff
Hormone-driven mechanisms in the central nervous system facilitate the analysis of mammalian behaviours
J. Endocrinol., Mar 2005; 184: 447 - 453.

Mark F. Banks, Evgenia V. Gerasimovskaya, Doug A. Tucker, Maria G. Frid, Todd C. Carpenter, and Kurt R. Stenmark
Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts
J Appl Physiol, Feb 2005; 98: 732 - 738.

Sara K. Hansen, Eva-Maria D. Nielsen, Jakob Ek, Gitte Andersen, Charlotte Glümer, Bendix Carstensen, Peter Mouritzen, Thomas Drivsholm, Knut Borch-Johnsen, Torben Jřrgensen, Torben Hansen, and Oluf Pedersen
Analysis of Separate and Combined Effects of Common Variation in KCNJ11 and PPARG on Risk of Type 2 Diabetes
J. Clin. Endocrinol. Metab., Jun 2005; 90: 3629 - 3637.

Hye Young Yi-Brunozzi and Stuart F. J. Le Grice
Investigating HIV-1 Polypurine Tract Geometry via Targeted Insertion of Abasic Lesions in the (–)-DNA Template and (+)-RNA Primer
J. Biol. Chem., May 2005; 280: 20154 - 20162.

Erika Brunet, Patrizia Alberti, Loďc Perrouault, Ravindra Babu, Jesper Wengel, and Carine Giovannangeli
Exploring Cellular Activity of Locked Nucleic Acid-modified Triplex-forming Oligonucleotides and Defining Its Molecular Basis
J. Biol. Chem., May 2005; 280: 20076 - 20085.

P Moore
Simplifying the probe set.
Nature, May 2005; 435(7039): 238.

BR Babu, PJ Hrdlicka, CJ McKenzie, and J Wengel
Optimized DNA targeting using N,N-bis(2-pyridylmethyl)-beta-alanyl 2'-amino-LNA.
Chem Commun (Camb), Apr 2005; (13): 1705-7.

Daniel A. Di Giusto, Wjatschesslaw A. Wlassoff, J. Justin Gooding, Barbara A. Messerle, and Garry C. King
Proximity extension of circular DNA aptamers with real-time protein detection
Nucleic Acids Res., Apr 2005; 33: 64.

L Hummelshoj, LP Ryder, HO Madsen, and LK Poulsen
Locked nucleic acid inhibits amplification of contaminating DNA in real-time PCR.
Biotechniques, Apr 2005; 38(4): 605-10.

Gitte Andersen, Lise Wegner, Dorit Packert Jensen, Charlotte Glümer, Lise Tarnow, Thomas Drivsholm, Pernille Poulsen, Sara Kristine Hansen, Eva-Maria Damsgaard Nielsen, Jakob Ek, Peter Mouritzen, Allan Vaag, Hans-Henrik Parving, Knut Borch-Johnsen, Torben Jřrgensen, Torben Hansen, and Oluf Pedersen
PGC-1 Gly482Ser Polymorphism Associates With Hypertension Among Danish Whites
Hypertension, Apr 2005; 45: 565 - 570.

Kees Fluiter, Miriam Frieden, Jeroen Vreijling, Christoph Rosenbohm, Marit B De Wissel, Signe M Christensen, Troels Koch, Henrik Orum, and Frank Baas
On the in vitro and in vivo Properties of Four Locked Nucleic Acid Nucleotides Incorporated into an Anti-H-Ras Antisense Oligonucleotide.
Chembiochem, Apr 2005; .

Barbara Saccŕ, Laurent Lacroix, and Jean-Louis Mergny
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
Nucleic Acids Res., Feb 2005; 33: 1182 - 1192.

EV Bichenkova, A Sardarian, HE Savage, C Rogert, and KT Douglas
An exciplex-based, target-assembled fluorescence system with inherently low background to probe for specific nucleic acid sequences.
Assay Drug Dev Technol, Feb 2005; 3(1): 39-46.

Joacim Elmén, Hĺkan Thonberg, Karl Ljungberg, Miriam Frieden, Majken Westergaard, Yunhe Xu, Britta Wahren, Zicai Liang, Henrik Řrum, Troels Koch, and Claes Wahlestedt
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality
Nucleic Acids Res., Jan 2005; 33: 439 - 447.

HM Pfundheller, AM Sorensen, C Lomholt, AM Johansen, T Koch, and J Wengel
Locked nucleic acid synthesis.
Methods Mol Biol, Jan 2005; 288: 127-46.

O Goldenberg, O Landt, RR Schumann, UB Gobel, and L Hamann
Use of locked nucleic acid oligonucleotides as hybridization/FRET probes for quantification of 16S rDNA by real-time PCR.
Biotechniques, Jan 2005; 38(1): 29-30, 32.

RA Op den Buijsch, JE de Vries, WJ Loots, O Landt, PA Wijnen, MP van Dieijen-Visser, and O Bekers
Genotyping of the PXR A11156C polymorphism with locked nucleic acid containing fluorogenic probes.
Pharmacogenomics J, Jan 2005; 5(2): 72-4.

Thierry D. Charlier, Gregory F. Ball, and Jacques Balthazart
Inhibition of Steroid Receptor Coactivator-1 Blocks Estrogen and Androgen Action on Male Sex Behavior and Associated Brain Plasticity
J. Neurosci., Jan 2005; 25: 906 - 913.

John J. Turner, Andrey A. Arzumanov, and Michael J. Gait
Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides
Nucleic Acids Res., Jan 2005; 33: 27 - 42.

PS Ng and DE Bergstrom
Alternative nucleic acid analogues for programmable assembly: hybridization of LNA to PNA.
Nano Lett, Jan 2005; 5(1): 107-11.

Yue-Ying Wang, Guang-Biao Zhou, Tong Yin, Bing Chen, Jing-Yi Shi, Wen-Xue Liang, Xiao-Long Jin, Jian-Hua You, Guang Yang, Zhi-Xiang Shen, Jue Chen, Shu-Min Xiong, Guo-Qiang Chen, Feng Xu, Yi-Wei Liu, Zhu Chen, and Sai-Juan Chen
AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec
PNAS, Jan 2005; 102: 1104 - 1109.

Douglas Horejsh, Federico Martini, Fabrizio Poccia, Giuseppe Ippolito, Antonino Di Caro, and Maria R. Capobianchi
A molecular beacon, bead-based assay for the detection of nucleic acids by flow cytometry
Nucleic Acids Res., Jan 2005; 33: 13.

Jean-Louis Mergny, Anne De Cian, Amar Ghelab, Barbara Saccŕ, and Laurent Lacroix
Kinetics of tetramolecular quadruplexes
Nucleic Acids Res., Jan 2005; 33: 81 - 94.

Elmen, HY Zhang, B Zuber, K Ljungberg, B Wahren, C Wahlestedt, and Z Liang
Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication.
FEBS Lett, Dec 2004; 578(3): 285-90.

Anna Válóczi, Csaba Hornyik, Nóra Varga, József Burgyán, Sakari Kauppinen, and Zoltán Havelda
Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes
Nucleic Acids Res., Dec 2004; 32: 175.

Hélčne Thomassin, Clémence Kress, and Thierry Grange
MethylQuant: a sensitive method for quantifying methylation of specific cytosines within the genome
Nucleic Acids Res., Dec 2004; 32: 168.

Omer Barad, Eti Meiri, Amir Avniel, Ranit Aharonov, Adi Barzilai, Isaac Bentwich, Uri Einav, Shlomit Gilad, Patrick Hurban, Yael Karov, Edward K. Lobenhofer, Eilon Sharon, Yoel M. Shiboleth, Marat Shtutman, Zvi Bentwich, and Paz Einat
MicroRNA expression detected by oligonucleotide microarrays: System establishment and expression profiling in human tissues
Genome Res., Dec 2004; 14: 2486 - 2494.


Newsletter

Keep up to date with our latest products - sign up to receive our Newsletter

New 2008 microRNA booklet



PrivacySitemapLegal