Exiqon - LNA for microRNA research - View list of microRNA photos

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Figure 1

Specific detection of miR-122a (top), miR-206 (middle) and miR-124a (bottom) using miRCURY™ detection probes in in situ hybridisation of whole mount zebrafish embryos.

The images were kindly provided by Dr. Ronald Plasterk, Hubrecht Laboratory, Th

Figure 2

Specific detection of mir-206 in Gallus gallus embryo with miRCURY™ in situ detection probe. mir-206 is expressed in all skeletal muscle cells, appearing at the onset of myogenic cell differentiation. At the pictured stage in embryonic development, mir-20

Specific detection of mir-206 in Gallus gallus embryo using a miRCURY™ LNA microRNA Detection probe. Mir-206 is expressed in all skeletal muscle cells, appearing at the onset of myogenic cell differentiation.

Figure 3

Detection of the liver specific miRNA-122a (red) in mouse cells using miRCURY™ detection probes. DNA is labeled with DAPI (in blue).

The image was kindly provided by Dr. Javier Martinez, IMBA - Institute of Molecular Biotechnology, Vienna, Austria

Figure 4

miR-124a expression in temporal isocortex of human brain detected in formalin-fixed, paraffin-embedded sections.

The image was kindly contributed by Dr. Zissimos Mourelatos, UPenn, Philadelphia, USA (Nelson PT et al, RNA, 12 (2) 2006).

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"I have tried three different techniques for detecting miRNAs by in situ hybridization in human brain tissue - they all failed. When I used the miRCURY probes from Exiqon employing a very simple technique, the protocol instantly and 'painlessly' succeeded. I am very pleased with the results"

says Dr. Peter Nelson from the Mourelatos Lab, UPenn, Philadelphia, PA, USA.

Download Nelson et al., RNA 2006 (264 KB)