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"We chose to use miRCURY LNA™ knockdown probes as we had previous experience with using LNA probes for in situ hybridisation with great success".

Amanda Dixon-McIver is finishing her Ph.D. under the supervision of Dr. Silvana Debernardi, in the Medical Oncology Laboratory headed by Prof. Bryan Young in the Institute of Cancer, Barts Hospital, in London, UK.

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Amanda Dixon-McIver


"Exiqon’s product is impressive. The procedures are easy to understand and very fast".

 
"the Power Labeling Kit is very fast, thus our samples are labeled and ready for hybridization in just half a day"
 
Dr. Xin Li, Cancer Research Institute of Southern Medical University in Guangzhou, China  
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“The miRCURY™ LNA microRNA PCR system is easy to use and provides high sensitivity and reproducibility.”
 
"It makes my validation faster, easier and more quantitative"
 
Scientist Louisa Cheung, Karolinska Institute, Sweden

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“Even microRNAs with a high level of similarity could be distinguished well using these arrays”

“The results show some differentially regulated miRNAs and a nice overlap of expression regarding miRNAs encoded by a common primary transcript.”

Dr. Roman-Ulrich Müller, Zentrale Klinishe Forschung, Uniklinik Freiburg.

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"The superior detection sensitivity eliminates the need for RNA size selection”

"More answers than questions when it comes to data analysis and interpretation."

Prof Martina Muckenthaler and Prof Matthias Hentze, University of Heidelberg and EMBL, Germany

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“We got some beautiful data and spectacular images”

"We generated a complete catalogue of images showing the temporal and spatial expression patterns of 115 conserved microRNAs in zebrafish embryos."

Prof Ronald H. A. Plasterk, Hubrecht Laboratory, The Netherlands

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“ProbeLibrary™: Reduced Assay Development Time - Improved Reproducibility”

"We can map everything to a particular region of a transcript and easily carry out cross validating assays, because several assays are available for the same transcript."

Dr Winston Patrick Kuo, Harvard Medical School, USA

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"ProbeLibrary™: Quick, specific, highly reproducible and cost effective"

"The ProbeLibrary™ has really sped up our research significantly: Assay design is extremely fast and reliable and all the Real-Time PCR probes are just in the freezer"
 
Dr Kiki Tahtis, University of Oxford, Cancer Research UK, United Kingdom.

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Nature Application Notes

MicroRNA profiling of breast cancer tissue (353 KB)
Functional studies of microRNA (301 KB)
MicroRNA expression profiling. (275 KB)


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