Figure 1. This graph shows the percentage of the capture probes that detect a given amount of synthetic microRNA. More than 90% of the miRCURY™ LNA Array capture probes detect 10 amol or less. More than 50% of the miRCURY™ LNA Array capture probes detect 1 amol or less.
Experimental setup: 705 synthetic microRNAs where labeled at 8 different concentrations in a background of 0.75?g tRNA and then hybridized to the array. Slopes were generated for all miRs, and the detection limit was defined as a signal >5x stdev from background